Publications

Peer-Reviewed Journal Articles

Volumetric single-molecule tracking inside subcellular structures. S. Daly, J.E. Chambers, C. Jones, B. Fu, J.D. Manton, J.S. Beckwith, S.J. Marciniak, D.C. Gershlick, S.F. Lee. Small (2026). DOI ⋅ PDF

3D super-resolution imaging of PSD95 reveals an abundance of diffuse protein supercomplexes in the mouse brain. S. Daly, K. Morris, E. Bulovaite, A. Handa, L. Muresan, A. Kitching, A. Spark, G. Chant, C. Adams, T. Kaizuka, K. O’Holleran, S.G.N. Grant, M.H. Horrocks, S.F. Lee. ACS Chemical Neuroscience (2025). DOI

Vortex light field microscopy: 3D spectral single-molecule imaging with a twist. B. Zhang, S. Daly, C. Zhu, M. Lenz, L.E. Weiss, L.M. Needham, R. Peters, S.F. Lee, K. O’Holleran. Optica (2024). DOI

POLCAM: Instant molecular orientation microscopy for the life sciences. E. Bruggeman, O. Zhang, L-M. Needham, M. Körbel, S. Daly, M. Cheetham, R. Peters, T. Wu, A.S. Klymchenko, S.J. Davis, E.K. Paluch, D. Klenerman, M.D. Lew, K. O’Holleran, S.F. Lee. Nature Methods (2024). DOI ⋅ PDF

High-density volumetric super-resolution microscopy. S. Daly, J.F. Fernandes, E. Bruggeman, A. Handa, R. Peters, S. Benaissa, B. Zhang, J.S. Beckwith, E.W. Sanders, R.R. Sims, D. Klenerman, S.J. Davis, K. O’Holleran, S.F. Lee. Nature Communications (2024). DOI ⋅ PDF

A comparative study of high-contrast fluorescence lifetime probes for imaging amyloid in tissue. F. Gorka, S. Daly, C.M. Pearson, E. Bulovaite, Y.P. Zhang, A. Handa, S.G.N. Grant, T.N. Snaddon, L-M. Needham, and S.F. Lee. Journal of Physical Chemistry B (2021). DOI ⋅ PDF

PhD Thesis

Advances in volumetric super-resolution microscopy and single-particle tracking. S. Daly. (2024). DOI ⋅ PDF